No particular dose adjustment recommended when tofacitinib coadministered with powerful CYP2C19 inhibitors; minimize tofacitinib dose if coadministered with equally average CYP3A4 and strong CYP2C19 inhibitors .Inhibition of platelet aggregation by clopidogrel is completely due to an Lively metabolite. Clopidogrel is metabolized to this Lively meta
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